Ketamine & IV Infusion Therapy for Pain in PA & NJ
IV infusion therapy, particularly ketamine and lidocaine infusions, has emerged as one of the most effective treatments for complex chronic pain conditions that have not responded to other therapies. Delaware Valley Pain & Spine Institute operates a full-service infusion center offering these treatments in a safe, monitored, clinical environment.
Ketamine works by blocking NMDA receptors in the brain, which are involved in central sensitization, the process that makes chronic pain self-sustaining. For conditions like CRPS and treatment-resistant depression, ketamine infusions can provide significant and lasting relief that other treatments cannot achieve.
Common Symptoms
- Patients seeking infusion therapy typically have CRPS or complex regional pain syndrome
- Chronic pain that has not responded to medications, injections, or other treatments
- Treatment-resistant depression with co-occurring chronic pain
- Neuropathic pain, burning, electric, or shooting nerve pain
- Fibromyalgia with severe central sensitization
- Phantom limb pain following amputation
Common Causes
- Central sensitization, the nervous system becomes hypersensitive, amplifying pain signals
- NMDA receptor dysfunction, the neurological pathway that ketamine targets
- Treatment-resistant conditions, pain or depression not responding to standard therapies
- Systemic inflammation, lidocaine infusions modulate inflammatory nerve signaling
Treatment Options at DVPSI
Our board-certified physicians use a stepwise, minimally invasive approach, always starting with the least invasive effective treatment and escalating only when necessary. Most patients find significant relief without major surgery.
Ketamine Infusion Series
A series of IV ketamine infusions (typically 4-6 over 2 weeks) to reset central sensitization. Each session is approximately 4 hours in our monitored infusion center.
Lidocaine Infusion
IV lidocaine has local anesthetic and anti-inflammatory properties that can provide meaningful relief for CRPS and neuropathic pain conditions.
Booster Infusions
Maintenance infusions after the initial series to sustain pain relief over time.
Combination Infusion Protocols
Individualized protocols combining ketamine and other agents based on your specific condition and response.
Comprehensive Pre-Infusion Evaluation
All infusion patients receive a thorough medical evaluation to determine appropriateness and optimize the treatment plan.
Why Choose DVPSI for Infusion Therapy Treatment
DVPSI was one of the early adopters of ketamine infusion therapy for CRPS in the Delaware Valley region. Our infusion center is staffed by physicians with anesthesiology training, ensuring the highest standard of monitoring and safety during all infusion procedures. We accept many insurance plans for infusion therapy, contact us for pre-authorization assistance.